منابع مشابه
Enhance transdermal delivery of flurbiprofen via microemulsions: Effects of different types of surfactants and cosurfactants
BACKGROUND AND THE PURPOSE OF THE STUDY Microemulsions are thermodynamically stable, clear dispersions of water, oil, surfactant, and cosurfactant. This study was aimed to develop flurbiprofen microemulsion for enhanced transdermal delivery and investigate the effects of different surfactants and cosurfactants on its delivery and phase behavior. METHOD Various surfactant-cosurfactant mixtures...
متن کاملDevelopment and Evaluation of Microemulsions for Transdermal Delivery of Insulin
Insulin-loaded microemulsions for transdermal delivery were developed using isopropyl myristate or oleic acid as the oil phase, Tween 80 as the surfactant, and isopropyl alcohol as the cosurfactant. The pseudoternary phase diagrams were constructed to determine the composition of microemulsions. The insulin permeation flux of microemulsions containing oleic acid as oil phase through excised mou...
متن کاملWater-in-oil microemulsions for effective transdermal delivery of proteins.
INTRODUCTION A water-in-oil microemulsion is a thermodynamically stable emulsion that has the capacity to 'hide' water-soluble molecules within a continuous oil phase. The very small size of the water droplets within the microemulsion means that these types of formulation can be applied topically to the skin, with the result that peptides and proteins can be delivered effectively into the derma...
متن کاملGreen synthesis via electrolysis in microemulsions*
Electrolysis in microemulsions is a promising approach for environmentally friendly chemical synthetic methods of the future. Employing microemulsions instead of organic solvents for electrosynthesis has the advantages of lower toxicity and cost, high dissolving power for reactants and mediators of unlike solubility, enhancement of reaction rates by controlling the reduction potentials of media...
متن کاملSynergistic Effect and Mechanism of Cineole and Terpineol on In-vitro Transdermal Delivery of Huperzine A from Microemulsions
The aim of the present study was to investigate the influence and the mechanisms of cineoleand terpineol on the in-vitro transdermal delivery of huperzine A from microemulsions, andtheir potential synergistic effect on the permeation enhancement. The transdermal deliveryof huperzine A from microemulsions with different concentrations of cineole and terpineolthrough the rat abdominal skin was de...
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ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2019
ISSN: 0975-7058
DOI: 10.22159/ijap.2019v11i2.30089